CovidSeniorV1, Main, Exploration, bibRecord, 000969

Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.

Identifieur interne : 000969 ( Main/Exploration ); précédent : 000968; suivant : 000970

Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.

Auteurs : Gerasimos N. Konstantinou [Canada] ; Jonathan Downar [Canada] ; Zafiris J. Daskalakis [Canada] ; Daniel M. Blumberger [Canada]

Source :

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [ 1545-7214 ] ; 2020.

RBID : pubmed:32753340

Descripteurs français

English descriptors

KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (epidemiology), Depressive Disorder, Major (psychology), Depressive Disorder, Major (therapy), Depressive Disorder, Treatment-Resistant (psychology), Depressive Disorder, Treatment-Resistant (therapy), Electroconvulsive Therapy (MeSH), Female (MeSH), Health Services Accessibility (MeSH), Humans (MeSH), Pandemics (MeSH), Patient Health Questionnaire (MeSH), Pneumonia, Viral (epidemiology), Transcranial Magnetic Stimulation (methods), Treatment Outcome (MeSH).
MESH :
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- methods : Transcranial Magnetic Stimulation.
- psychology : Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant.
- therapy : Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant.
- Aged, Betacoronavirus, Electroconvulsive Therapy, Female, Health Services Accessibility, Humans, Pandemics, Patient Health Questionnaire, Treatment Outcome.

Abstract

OBJECTIVE

Electroconvulsive therapy (ECT) is an essential psychiatric service with an important role in treating older adults with severe or treatment-resistant depression. During the COVID-19 pandemic, ECT services have be constrained by infection control measures. We report a case of a 66-year-old female patient with a severe major depressive episode who had previously responded to right unilateral ECT and was treated with two modified accelerated intermittent theta-burst stimulation (aiTBS) protocols.

METHODS

The two aiTBS courses consisted of eight daily sessions over five consecutive days, followed by gradual tapering, using 1,800 pulses per session pre-COVID-19 (first course), and 600 pulses per session during the pandemic (second course).

RESULTS

Moderate to severe baseline depressive symptoms reached remission levels after both courses.

CONCLUSION

The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.

DOI: 10.1016/j.jagp.2020.07.007
PubMed: 32753340
PubMed Central: PMC7362844

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000829
to stream Main, to step Curation: 000829

Le document en format XML

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<term>Depressive Disorder, Major (psychology)</term>
<term>Depressive Disorder, Major (therapy)</term>
<term>Depressive Disorder, Treatment-Resistant (psychology)</term>
<term>Depressive Disorder, Treatment-Resistant (therapy)</term>
<term>Electroconvulsive Therapy (MeSH)</term>
<term>Female (MeSH)</term>
<term>Health Services Accessibility (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Patient Health Questionnaire (MeSH)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Transcranial Magnetic Stimulation (methods)</term>
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<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Questionnaire de santé du patient (MeSH)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Stimulation magnétique transcrânienne (méthodes)</term>
<term>Sujet âgé (MeSH)</term>
<term>Trouble dépressif majeur (psychologie)</term>
<term>Trouble dépressif majeur (thérapie)</term>
<term>Trouble dépressif résistant aux traitements (psychologie)</term>
<term>Trouble dépressif résistant aux traitements (thérapie)</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
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<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Trouble dépressif majeur</term>
<term>Trouble dépressif résistant aux traitements</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Depressive Disorder, Major</term>
<term>Depressive Disorder, Treatment-Resistant</term>
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<term>Depressive Disorder, Treatment-Resistant</term>
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<term>Trouble dépressif résistant aux traitements</term>
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<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Betacoronavirus</term>
<term>Electroconvulsive Therapy</term>
<term>Female</term>
<term>Health Services Accessibility</term>
<term>Humans</term>
<term>Pandemics</term>
<term>Patient Health Questionnaire</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>Electroconvulsive therapy (ECT) is an essential psychiatric service with an important role in treating older adults with severe or treatment-resistant depression. During the COVID-19 pandemic, ECT services have be constrained by infection control measures. We report a case of a 66-year-old female patient with a severe major depressive episode who had previously responded to right unilateral ECT and was treated with two modified accelerated intermittent theta-burst stimulation (aiTBS) protocols.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>The two aiTBS courses consisted of eight daily sessions over five consecutive days, followed by gradual tapering, using 1,800 pulses per session pre-COVID-19 (first course), and 600 pulses per session during the pandemic (second course).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Moderate to severe baseline depressive symptoms reached remission levels after both courses.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.</p>
</div>
</front>
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Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.

Accelerated Intermittent Theta Burst Stimulation in Late-Life Depression: A Possible Option for Older Depressed Adults in Need of ECT During the COVID-19 Pandemic.

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